Photo by Bill Dillard
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Our top choices for Southeast Missouri hotels
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (62 reviews)
"I had a great time with my mom there!"
Lily
The price is AU$209
includes taxes & fees
29 Apr - 30 Apr
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (177 reviews)
"Nice room, good breakfast "
KENNETH
The price is AU$146
includes taxes & fees
10 May - 11 May
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,002 reviews)
"Most catering to people staying there than any other properties we have stayed on our trip."
Ruth
The price is AU$118
includes taxes & fees
25 May - 26 May
Echo Bluff State Park
Echo Bluff State ParkEminence
9.4 out of 10, Exceptional, (244 reviews)
"Always a wonderful experience when staying here"
James
The price is AU$242
includes taxes & fees
28 Apr - 29 Apr
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (347 reviews)
"Room was clean and near the handicap ramp. Staff was very helpful. "
Kandy
The price is AU$145
includes taxes & fees
29 Apr - 30 Apr
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (122 reviews)
"Hotel was very clean, quiet and has a great location! "
Dustin
The price is AU$155
includes taxes & fees
4 May - 5 May
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,003 reviews)
"Hotel was nice and staff was quite helpful!"
Linda
The price is AU$158
includes taxes & fees
3 May - 4 May
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (580 reviews)
"Stay was amazing. Beds were very comfortable, rooms were super clean and staff was very helpful. "
Craig
The price is AU$162
includes taxes & fees
10 May - 11 May
Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (825 reviews)
"Great breakfast and friendly staff. Very pet friendly."
Timothy
The price is AU$152
includes taxes & fees
17 May - 18 May
Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.4 out of 10, Exceptional, (311 reviews)
"Every thang was awsome and it has been the nicest place we have stayed very well taken care of"
Terry
The price is AU$165
includes taxes & fees
29 Apr - 30 Apr
Arcadia Academy
Arcadia AcademyArcadia
9.8 out of 10, Exceptional, (12 reviews)
"We enjoyed ourselves we've been to plenty of places but we had a great excellent time people the room the food and it was great we will be back¡!!!"
John
The price is AU$207
includes taxes & fees
3 May - 4 May
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)Sikeston
8.4 out of 10, Very good, (769 reviews)
"Breakfast was adequate room was clean."
Daniel
The price is AU$96
includes taxes & fees
8 May - 9 May
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.6 out of 10, Exceptional, (1,005 reviews)
"Nice place to stay"
Lance
The price is AU$164
includes taxes & fees
4 May - 5 May
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (890 reviews)
"Staff is Great , Room very clean and well stocked ."
joan
The price is AU$174
includes taxes & fees
4 May - 5 May
The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (558 reviews)
"Really nice and clean rooms. Staff was super friendly and let me check in 2 hours early because my neck had been bothering me and i needed to lay down"
Raun
The price is AU$186
includes taxes & fees
11 May - 12 May
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (72 reviews)
"The breakfast was good, the service was good, and the staff was very friendly"
Angela
The price is AU$174
includes taxes & fees
17 May - 18 May
EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.6 out of 10, Exceptional, (88 reviews)
"Parking was easy. The staff were super friendly and helpful. Room was nice and comfortable. I definetely recommend staying here if you are in this area."
Mehdi
The price is AU$128
includes taxes & fees
11 May - 12 May
Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
10.0 out of 10, Exceptional, (22 reviews)
"Great stay "
Ashley
The price is AU$166
includes taxes & fees
4 May - 5 May
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (754 reviews)
"Property was easily accessible and very clean!!"
Denise
The price is AU$135
includes taxes & fees
30 Apr - 1 May
The Farmstead Hotel
The Farmstead HotelCaruthersville
8.6 out of 10, Excellent, (542 reviews)
"Such a wonderful hotel! I highly recommend staying here. I’ve been there multiple times and I’ve never once been disappointed. "
Alexus
The price is AU$151
includes taxes & fees
28 Apr - 29 Apr
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
9.8 out of 10, Exceptional, (62 reviews)
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Stay near popular Central United States attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Recent Reviews in Southeast Missouri
Holiday Inn Poplar Bluff by IHG
10/10 Excellent
More cheap accommodation in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
The price is AU$94 per night from 24 May to 25 May
AU$94
24 May - 25 May
includes taxes & fees
8/10 Very Good! (1,006 reviews)
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