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20 July - 21 July
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25 July - 27 July
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Top hotels and accommodation in Southeast Missouri

Postcard Cabins St. Francois
Situated in a wooded area, this cabin features a cozy outdoor space with a porch, bench, fire pit, and table.

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (17)
"Had a wonderful time"
The price is AU$205
includes taxes & fees
21 July - 22 July
Postcard Cabins St. Francois
Pear Tree Inn Sikeston
Relax in the spacious lobby with a mezzanine level, comfortable seating, and large windows.

Pear Tree Inn Sikeston

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Great place to stay with kids "
The price is AU$141
includes taxes & fees
21 July - 22 July
Pear Tree Inn Sikeston
Drury Inn & Suites Sikeston, MO
Relax in the serene courtyard, surrounded by lush greenery and comfortable seating.

Drury Inn & Suites Sikeston, MO

3.0 star property
9.4 out of 10, Exceptional, (1004)
"Will stay again"
The price is AU$180
includes taxes & fees
27 July - 28 July
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Cape Girardeau
Reception area with a reception desk, flat-screen TV, and seating area.

Drury Inn & Suites Cape Girardeau

3.0 star property
9.4 out of 10, Exceptional, (960)
"Room was very clean and staff was excellent!"
The price is AU$156
includes taxes & fees
25 July - 26 July
Drury Inn & Suites Cape Girardeau
Drury Inn & Suites Jackson MO
Relax in the hotel's spacious lobby, featuring a comfortable seating area with a sofa, coffee tables, and chairs.

Drury Inn & Suites Jackson MO

3.0 star property
9.6 out of 10, Exceptional, (1002)
"Great breakfast!"
The price is AU$146
includes taxes & fees
24 July - 25 July
Drury Inn & Suites Jackson MO
Microtel Inn & Suites by Wyndham Sainte Genevieve
Relax in this stylish room with two single beds, a flat-screen TV, and a desk for work or relaxation.

Microtel Inn & Suites by Wyndham Sainte Genevieve

2.5 star property
8.8 out of 10, Excellent, (580)
"Clean and affordable "
The price is AU$153
includes taxes & fees
17 Aug - 18 Aug
Microtel Inn & Suites by Wyndham Sainte Genevieve
The Riverview
Relax in a stylish room with two beds, a desk, and a city view.

The Riverview

2.0 star property
9.4 out of 10, Exceptional, (349)
"Wonderful place to stay. Very clean and affordable!"
The price is AU$183
includes taxes & fees
21 July - 22 July
The Riverview
Pear Tree Inn Cape Girardeau West
Welcome to our reception area, featuring a modern reception desk and a cozy seating area with armchairs.

Pear Tree Inn Cape Girardeau West

2.5 star property
9.0 out of 10, Wonderful, (1005)
"The beds were comfortable "
The price is AU$121
includes taxes & fees
21 July - 22 July
Pear Tree Inn Cape Girardeau West
The Farmstead Hotel
Welcome to The Farmstead, where a symmetrical facade and central entrance invite you in.

The Farmstead Hotel

2.5 star property
8.8 out of 10, Excellent, (384)
"Great stay!"
The price is AU$153
includes taxes & fees
26 July - 27 July
The Farmstead Hotel
Hampton Inn Poplar Bluff
Relax in the serene patio area surrounded by lush greenery and a charming gazebo.

Hampton Inn Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (741)
"Excellent property, great location. "
The price is AU$167
includes taxes & fees
17 Aug - 18 Aug
Hampton Inn Poplar Bluff
Pear Tree Inn Cape Girardeau Near the Medical Center
Enjoy meals in the dining area with a view, featuring a long counter, TV, and comfortable seating options.

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
9.0 out of 10, Wonderful, (1004)
"Excellent place to stay "
The price is AU$121
includes taxes & fees
21 July - 22 July
Pear Tree Inn Cape Girardeau Near the Medical Center
The Wildwood Hotel
Enjoy a romantic dinner for two with fine china, linens, and elegant table settings.

The Wildwood Hotel

3.5 star property
9.2 out of 10, Wonderful, (1552)
"Great location for our stay"
The Wildwood Hotel
Tru By Hilton Cape Girardeau
Enjoy a spacious room with a large bed, desk, and seating area, featuring a flat-screen TV and a desk lamp.

Tru By Hilton Cape Girardeau

2.5 star property
9.6 out of 10, Exceptional, (44)
"Nice quiet place to stay, staff was super polite"
The price is AU$162
includes taxes & fees
27 July - 28 July
Tru By Hilton Cape Girardeau
Fairfield Inn & Suites by Marriott Sikeston
Bar (on property)

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
10.0 out of 10, Exceptional, (14)
"Nice hotel "
The price is AU$183
includes taxes & fees
27 July - 28 July
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott Poplar Bluff
Relax in the spacious lobby with a stone fireplace, comfortable seating, and a large window.

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
9.4 out of 10, Exceptional, (774)
"Great location. Property well maintained. "
The price is AU$172
includes taxes & fees
3 Aug - 4 Aug
Fairfield Inn & Suites by Marriott Poplar Bluff
Baymont Inn and Suites by Wyndham Farmington, MO
Welcome to our reception area, where guests can check in and relax in a comfortable seating area.

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very good, (1007)
"Nice place and fairly cheap"
The price is AU$98
includes taxes & fees
3 Aug - 4 Aug
Baymont Inn and Suites by Wyndham Farmington, MO
Hampton Inn Cape Girardeau I 55 East
Relax in style with comfortable seating and social tables amidst a clean, modern space.

Hampton Inn Cape Girardeau I 55 East

2.5 star property
9.6 out of 10, Exceptional, (728)
"Close distance to good restaurants "
The price is AU$190
includes taxes & fees
27 July - 28 July
Hampton Inn Cape Girardeau I 55 East
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Relax in the stylish lobby, featuring a fireplace, comfortable seating, and a large flat-screen TV.

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
9.4 out of 10, Exceptional, (1002)
"Great place to stay. "
The price is AU$175
includes taxes & fees
8 Aug - 9 Aug
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express & Suites Perryville by IHG
Welcome to our reception area, where guests can check in at the digital station and enjoy the vibrant artwork.

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
9.4 out of 10, Exceptional, (485)
"Good place "
The price is AU$185
includes taxes & fees
14 Aug - 15 Aug
Holiday Inn Express & Suites Perryville by IHG
Drury Inn & Suites Hayti Caruthersville
Relax in our spacious lobby with a seating area, fireplace, and stunning views.

Drury Inn & Suites Hayti Caruthersville

3.0 star property
9.4 out of 10, Exceptional, (1002)
"Great stay!"
The price is AU$165
includes taxes & fees
2 Aug - 3 Aug
Drury Inn & Suites Hayti Caruthersville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:1 Aug - 3 Aug

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Mini-golf

Wilderness Lodge

3.0 star property
Lesterville
9.6/10Exceptional (29 reviews)
10% off
Price is AU$760
AU$380 per night
includes taxes & fees
Wilderness Lodge
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Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.

See all hotels in Southeast Missouri

Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Enjoyed everything "
Marvin 1-night trip
Posted 1 day ago
Drury Inn & Suites Sikeston, MO